The talk will cover rather broadly related issues - the priming of syntactic structures and the processing of syntactic variation. The experimental technique of syntactic priming is based on the phenomenon that people tend to reuse sentence structures and is used to explore the reality of mental linguistic representations - what can be primed must play a role psychologically. However, it is still unclear which information exactly can be primed. I will present a picture-description study which aimed to contribute to the disentangling of this puzzle by priming structures different in word order while controlling for other potentially relevant structures (i.e. syntactic categories and animacy). The second part of the talk will deal with the comprehension of syntactic variation. Languages provide different kinds of syntactic alternatives (e.g., word orders and alternations). Linguistically, a lot of work has been done on the kinds and importance of constraints regulating the choice between these variants. From a cognitive perspective, it is interesting to study the difference in processing effort for the different structures as well as the interaction of different constraints (e.g., in terms of licensing unpreferred variants and anticipating upcoming referents). I will present experimental possibilities for testing some of these interactions.